Project supported by the European Commission
Sixth framework programme - contract n° 018673
and by the Regional Council of Ile-De-France
Coordination: INRA
A first step to regenerative medicine is to find a means to cause controlled de-differentiation of adult tissue. Plurigenes aims at achieving major breakthroughs in the discovery and understanding of the function of genes controlling pluripotency in the central nervous system. These later could enable the de-differentiation of terminally differentiated neural cells into pluripotent cells through transgenesis, a goal that fully meets the requirements of LSH-2004-1.1.0-1.
Plurigenes will start by identifying candidate genes in model organisms, following original approaches involving screens performed by in situ hybridations on well-characterised neural structures or by gain of function analysis. As pointed out in LSH-2004-1.1.0-1, innovative technologies of transgenesis and imaging in several model organisms will be settled to reach this goal.
The news
Sep-20-2007- Next Plurigenes event
The next meeting of Plurigenes will take place in England in the London's area (near Stansted airport) the next 24, 25 September 2007.
More informations
May-11-2007- Welcome on the first version of the Plurigenes website
First version of the Plurigenes website is launched today.